Our Science

Saving Lives with Therapies from Platelets

Cellphire Therapeutics, Inc. (“Cellphire”) is a clinical stage biotechnology company with a portfolio of novel, stabilized, allogeneic, platelet-derived, cellular therapeutics addressing markets in > $4 Billion.  Benefiting from significant historical and planned funding from the US Government, our therapeutics utilize proprietary process and formulation technologies.  

Cellphire has two technologies in Phase 2 clinical trials, Freeze-dried Platelet-derived Hemostat (FPH), a stabilized platelet-derived biologic, and Cryopreserved Platelets (CPP).

Lead Investigational Products

Thrombosomes Product
Freeze-dried Platelet-derived Hemostatic (FPH)
CLPH-211, Perioperative Hemostatic Agent, the lead Freeze-dried Platelet-derived hemostatic (FPH) technology product. The Denmark Phase 2 clinical trials completed enrollment in March 2024 with top line data available in Q2 2024.  With 70 human exposures, CLPH-211 has strong clinical safety data with significant, additional pre-clinical safety data. The product has 3+ year room temperature stability and simple rehydration with sterile water in minutes. CLPH-211 benefits from Biomedical Advanced Research and Development Authority (BARDA) and the Department of Defense (Army) support due to the mission fit.
Learn more
CPP Product
Cryopreserved Platelets (CPP)
Cryopreserved Platelets (CLPH-511), the furthest advanced product in the portfolio, utilizes cryopreservation of platelets (CPP).  Put on the MPAC list in October 2023, this critical program is in a Phase 2/3 clinical trial. Addressing liquid stored platelet (LSP) availability challenges for rural and field hospitals. Targeting BLA in 2027, CLPH-511’s development is substantively funded by the Department of Defense. CPP is comprised of frozen platelets stabilized with a cryoprotectant, DMSO (dimethyl sulfoxide). CPP can be cryopreserved for up to 5 years, unlike standard platelets which can only be stored for 5 to 7 days.
Learn more

Want to hear more about our trials and research?

Thank you! Your submission has been received!
Oops! Something went wrong while submitting the form.