Our Science

Platelets: Frozen and Freeze-Dried Current Products in Development and Regulatory Licensing Challenges

Pidcoke H., Kelly K., Fitzpatrick G.M., Dumont L.J.

Damage Control Resuscitation

January 2020

Novel platelet products under development for the treatment of thrombocytopenia or acute hemorrhage

Michael Fitzpatrick G.

Transfusion and Apheresis Science: Official Journal of the World Apheresis Association: Official Journal of the European
Society for Haemapheresis

February 2019

Safety evaluation of a lyophilized platelet-derived hemostatic product

Jeffrey Barroso; Barbara Osborne; Gayle Teramura; Esther Pellham; Michael Fitzpatrick; Ruth Biehl; Anna Yu; Joan Pehta; Sherrill J. Slichter

Transfusion

December 2018

Dried Platelets in a Swine Model of Liver Injury

Kenji Inaba; Galinos Barmparas; Peter Rhee; Bernardino C. Branco; Michael Fitzpatrick; Obi T. Okoye; Demetrios Demetriades

Shock

May 2014

Thrombosomes: a platelet-derived hemostatic agent for control of noncompressible hemorrhage

G. Michael Fitzpatrick; Richard Cliff; Narendra Tandon

Transfusion

January 2013

Lyophilised reconstituted human platelets increase thrombus formation in a clinical ex vivo model of deep arterial injury

G. Michael Fitzpatrick; Richard Cliff; Narendra Tandon

Transfusion

January 2013

Trehalose stabilized freeze-dried human platelets, Thrombosomes, reduce blood loss in Thrombocytopenic rabbit ear bleed model by as much as 89.5%

Fitzpatrick G; Vibhudatta A; Agashe H; Dee J.

Vox Sanguinis

July 2010

Trehalose stabilized freeze-dried human platelets, Thrombosomes®, express surface markers, thromboelastogram (teg) values and size distribution similar to two to three-day old stored platelets

Fitzpatrick G; Dee J; Cliff R

Vox Sanguinis

July 2010

Trehalose stabilized freeze-dried human platelets, Thrombosomes®, persist in circulation 24 hours after infusion and are non-immunogenic in New Zealand white rabbits

Fitzpatrick G; Vibhudatta A; Agashe H; Phillips W; Goins B; Dee J; Cliff R

Vox Sanguinis

July 2010

Temporal growth factor release from platelet-rich plasma, trehalose lyophilized platelets, and bone marrow aspirate and their effect on tendon and ligament gene expression

Taralyn McCarrel; Lisa Fortier

Journal of Orthopaedic Research

August 2009

Wound-healing properties of trehalose-stabilized freeze-dried outdated platelets

Wound-healing properties of trehalose-stabilized freeze-dried outdated plateletsRuth Sum; Sarah Hager; Giorgio Pietramaggiori; Dennis P. Orgill; Josh Dee; Alan Rudolph; Cindy Orser; G. Michael Fitzpatrick; David Ho

Transfusion

April 2007

Trehalose lyophilized platelets for wound healing

Giorgio Pietramaggiori, MD; Arja Kaipainen, MD, PhD; David Ho, PhD; Cindy Orser, PhD; Walter Pebley, PE; Alan Rudolph, PhD, MBA; Dennis P. Orgill, MD, PhD

Wound Repair and Regeneration

March 2007

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