Active, Recruiting
This is a Phase 2 clinical trial to evaluate safety and efficacy of cryopreserved platelets (CPP) vs. liquid stored platelets in controlling blood loss in patients undergoing cardiopulmonary bypass surgery.
CPP are frozen platelets stabilized with Dimethyl Sulfoxide (DMSO), which can be stored frozen for 5 years, unlike standard liquid stored platelets which can only be stored for 5 to 7 days. Learn more about CPP
This objective of this trial is to compare the amount of bleeding that occurs during and after cardiopulmonary bypass surgery in patients who receive standard-of-care liquid stored platelets versus patients who receive the investigational product, CPP. Approximately 200 volunteer patients will be recruited to take part in this study at a number of locations in the United States.
Study Start Date
September 2021
Estimated Primary Completion Date
October 2023
Estimated Study Completion Date
April 2024
Only a qualified healthcare professional can determine your eligibility. However, this information may be useful in talking with your doctor.
Age
Adults, 18 or older
Gender
All
Condition
Cardiopulmonary bypass surgery
Trial sites will be added as they are recruited.
Maine Medical Center
Oklahoma University Medical Center
Dartmouth‐Hitchcock Medical Center
University of Maryland Medical Center
The Ohio State University, Wexner Medical Center
University of Alabama
University of Florida Health
University of Colorado
University of Virginia
Oregon Health and Science University
George Washington University
Abington Memorial Hospital
Johns Hopkins Hospital
Duke University Hospital
Thomas Jefferson University Hospital
INOVA Heart and Vascular Institute
If you think you might be eligible and are interested in this study, please talk to your doctor.
Participating in a clinical trial is an important decision. Anyone participating in a trial should know as much as possible about what is being studied, what risks are involved, and what potential benefits may be gained before deciding to enroll.
Find out more in our Clinical Trials FAQ